31 articles - From Friday Aug 26 2022 to Friday Sep 02 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Am J Clin Nutr |
Preventive small-quantity lipid-based nutrient supplements reduce severe wasting and severe stunting among young children: an individual participant data meta-analysis of randomized controlled trials. Including SQ-LNS in preventive interventions to promote healthy child growth and development is likely to reduce rates of severe wasting and stunting. Registered at as CRD42019146592. |
| Inflamm Bowel Dis |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
Absorption of iron from edible house crickets: a randomized cross-over stable isotope study in humans. Iron absorption from house crickets and fortified maize porridge with crickets is low, which may be explained by the presence of chitin and other inhibitors in the cricket biomass. This study was registered in the Netherlands Trial Register, study was registered in the Netherlands Trial Register, Trial ID NL6821, source ID NL59400.081.16, |
Coffee consumption and risk of endometrial cancer: a pooled analysis of individual participant data in the Epidemiology of Endometrial Cancer Consortium (E2C2). The results of the largest analysis to date pooling individual-level data further support the potentially beneficial health effects of coffee consumption in relation to EC, especially among females with higher BMI. |
Diet, but not food type, significantly affects micronutrient and toxic metal profiles in urine and/or plasma; a randomized, controlled intervention trial. Although small effects of food type cannot be ruled out, our study suggests that only changing to a MedDiet with higher fruit and vegetable, and lower meat consumption results in a large increase in phenolic and mineral micronutrient intake. |
Dietary Potassium Intake, Kidney Function, and Survival in a Nationally Representative Cohort. Lower dietary potassium scaled to energy intake was associated with higher mortality, irrespective of kidney function. There was also synergistic relationship between higher potassium intake, plant-based sources, and macronutrient/mineral consumption with survival. Further studies are needed to elucidate pathways linking potassium intake and co-existing dietary factors with survival in populations with and without CKD. |
Healthy dietary patterns and risk of cardiovascular disease in US Hispanics/Latinos: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Although adherence to healthy eating patterns varies by Hispanic/Latino backgrounds and generations, greater adherence to these eating patterns is associated with lower risk of CVD across diverse US Hispanics/Latinos. |
Iron Metabolism Regulation in Females and Males Exposed to Simulated Microgravity: results from the Randomized Trial AGBRESA. The data from this exploratory study suggest that 1) AG training does not influence the iron metabolism responses to microgravity; 2) iron metabolism parameters, especially iron availability for cells, are significantly increased in males, but not in females, exposed to long-term simulated microgravity. Due to the small sample size of females, we nevertheless must be cautious before concluding that iron metabolism could differently respond to microgravity in females. Clinical trial registry number DRKS00015677. |
The Human Gut Microbiota and Glucose Metabolism: a Scoping Review of Key Bacteria and the Potential Role of Short Chain Fatty Acids. We conclude that observational studies applying metagenomics sequencing to identify species-level relationships are warranted, as are studies accounting for confounding factors and investigating SCFA and postprandial glucose metabolism. Such advances in the field will, together with mechanistic and prospective studies and investigations into diet-gut microbiota interactions, have the potential to bring critical insight into roles of gut microbiota and microbial metabolites in human glucose metabolism and to contribute towards the development of novel prevention strategies for type 2 diabetes, including precision nutrition. |
Top sources and trends in consumption of total energy and energy from solid fats and added sugars among youth 2-18 years: United States 2009-2018. In 2015-2018, SOFAS contributed over 30% of total energy for ages 2-18 years, which doubled the Dietary Guidelines for Americans' recommended limit of 15%. Top five sources of total energy were similar to those of solid fats, and those of SOFAs similar to those of added sugars. These results may inform public health efforts for improving diet quality. |
Vitamin D status and prevalence of metabolic syndrome by race and Hispanic origin in U.S. adults: findings from 2007-2014 NHANES. Lower Vitamin D status was significantly associated with MetS among U.S. adults after adjusting for sociodemographic and lifestyle factors, dietary supplement use, and BMI. This finding was noted across al race and Hispanic origin groups, although the strength of the association varied being strongest for non-Hispanic White adults. |
| Inflamm Bowel Dis |
Aeroallergen-related Diseases Predate the Diagnosis of Inflammatory Bowel Disease. The association between asthma, AR, and IBD suggest the possibility that whatever triggers the onset of these atopic diseases may trigger the onset of IBD as well, and aeroallergens are plausible culprits. |
Quantitative Fecal Microbiota Profiles Relate to Therapy Response During Induction With Tumor Necrosis Factor a Antagonist Infliximab in Pediatric Inflammatory Bowel Disease. High absolute abundance of Bifidobacteriales in the gut microbiota of pediatric patients reflects anti-inflammatory characteristics associated with rapid response to therapy. This warrants further studies on whether modification of pretreatment microbiota might improve the outcomes. |
Use of IBD Drugs in Patients With Hepatobiliary Comorbidities: Tips and Tricks. Data from the literature suggest a safe hepatobiliary profile of biologic agents and small molecules in the case of nonalcoholic fatty liver disease, autoimmune hepatitis, primary sclerosing cholangitis, primary biliary cholangitis, and portal vein thrombosis. Consequently, although the liver disease does not affect a different therapeutic approach in patients with concomitant IBD and liver disease, a close risk/benefit analysis for each drug should be performed in these patients, especially in cirrhotic patients and in the postliver transplant setting. |
| J Crohns Colitis |
Analysis of systemic epigenetic alterations in inflammatory bowel disease: defining geographical, genetic, and immune-inflammatory influences on the circulating methylome. These data demonstrate consistent epigenetic alterations at diagnosis in European patients with IBD, providing insights into the pathogenetic importance and translational potential of epigenetic mapping in complex disease. |
Proteomic analysis identifies three reliable biomarkers of intestinal inflammation in the stools of patients with Inflammatory Bowel Disease. we show for the first time that the 2-DIGE is a reliable method to detect proteins in the human stools. Three novel fecal biomarkers of gut inflammation have been identified that display good specificity and sensitivity for identify IBD and significantly correlate with IBD severity. |
| Liver Transpl |
Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis. Microbial-metabolomic correlations were more complex, dense, and homogeneous among those who developed NIs, indicating greater linkage strength. Serum metabolites and gut microbiota on admission are associated with NI development in cirrhosis. |
Evaluation of Liver Stiffness Measurement Based Scores in Liver Transplant Recipients. The LSM based scores do not improve the diagnostic performance of LSM alone in LT recipients for detection of advanced fibrosis. This results from the impact of immunosuppression on bio-clinical profile and underscores the importance of developing LSM-based scores that are specific to LT patients. |
Role of extracorporeal membrane oxygenation as a salvage therapy for liver transplant recipients in a high-volume transplant center. The outcomes of adult OLT recipients with ECMO treatment were acceptable in terms of weaning success and survival until hospital discharge. This study confirmed that ECMO treatment for OLT recipients with septic shock and elevated bilirubin levels might be associated with a higher in-hospital mortality and demonstrated the importance of a multidisciplinary ECMO team approach. |
| Pancreatology |
Double deficiency of cathepsin B and L in the mouse pancreas alters trypsin activity without affecting acute pancreatitis severity. Double deletion of Ctsb and Ctsl in the mouse pancreas altered intrapancreatic trypsin activity but did not affect disease severity and inflammatory response after cerulein-induced AP. |
Integrative transcriptomic analysis identifies a novel gene signature to predict prognosis of pancreatic cancer in different subtypes. The integrative transcriptomic analysis identifies a consensus gene signature that can discriminate pancreatic cancer subtypes and determine patient prognosis by evaluating the genomic reprogramming and the level of immune infiltration profile in pancreatic cancer. |
White matter brain changes in chronic pancreatitis: A 7-year longitudinal follow-up study. Individuals with CP had widespread cerebral white matter alterations at baseline that can likely be explained by the CP disease and exposure to toxic substances. Otherwise, further progression resembles that in healthy controls. |
Plenty of the editorials are available as full text through the publisher website using the provided link
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Clin Nutr |
| J Crohns Colitis |
| Liver Transpl |
Letters to the editors and authors’ replies